Having faltered in November, Spurs have now won three on the bounce in all competitions and go into the encounter at the Etihad fourth in the standings, some 18 points off their rivals.
"I am so positive. I am a positive person. What happens on Saturday, who knows?" Pochettino told Sky Sports News after his side's 2-0 win over Brighton & Hove Albion at Wembley last night. "We go to Manchester to try to win. Football is football. In the last week, we have got three wins, and that is so important for us. We now feel we can stay higher in the table. There is a long way to go in the season and anything can happen.
"We are going to enjoy the game, as it is a fantastic challenge to play Manchester City. They are the best team in England, and one of the best teams in Europe. I am so excited to play in these games. I like to play against these teams, against managers like [Pep] Guardiola."
Spurs have taken just four points from their four games against top-six opposition so far this term.