Pochettino was appointed as the new manager at White Hart Lane this summer, replacing Tim Sherwood, who led the side to a sixth-placed finish in the Premier League last season.
After suffering injury problems, Dembele struggled to perform under Sherwood, but the Belgium international is looking forward to working with Pochettino after his impressive work at Southampton.
"I have heard a lot of good stories about Pochettino so I hope it will be a good appointment," said Dembele in The Sun. "The style Southampton played under him was very impressive. Let's hope it is going to be the same at Tottenham as well.
"Of course it's good to have a change and a fresh start. We have a very good group of players and if we have a very good manager as well, then we can do big things.
"I hope I can fit in well under the new manager but we have to know what his plans are first."
Dembele is currently at the World Cup with the Belgium national team.