Ryan Bertrand has withdrawn from the England squad for the upcoming friendlies with the Netherlands and Italy due to a back injury.
The Southampton left-back has 19 caps for the Three Lions and started five of the nation's past six World Cup qualifiers.
An FA statement confirmed: "There's been an update to the Three Lions squad, with Ryan Bertrand returning to Southampton for further assessment on a back issue.
"Bertrand's withdrawal is a precautionary measure, but he won't play in this month's matches."
Bertrand played 90 minutes in Southampton's 2-0 win over Wigan Athletic in Sunday's FA Cup quarter-final at the DW Stadium.