The Owls will be hoping to establish a strong record at home following their tense 3-2 win over Birmingham City on Tuesday, while Millwall will try to rely on their current away form after they clinched a 2-1 victory over Peterborough United earlier this week.
Dave Jones is likely to stick to a similar starting lineup that defeated Birmingham on Tuesday. However, Gary Madine may come in for Barcelona loan signing Rodri, who could start on the bench following his run-out against the Blues.
Sheffield Wednesday: Kirkland; Buxton, R Johnson, Beevers, Llera; Semedo, Antonio, J Johnson, McCabe; O'Grady, Rodri
Millwall: M Taylor; Dunne, Lowry, Osborne, Malone; Wright, Trotter, Henry, Abdou; Henderson, Keogh
Sports Mole says: 1-1