Sevilla enjoyed an excellent 2019-20 campaign as they finished fourth in La Liga in addition to winning the Europa League, but it would be fair to say that their league form this season has been disappointing.
Three wins, one draw and three defeats - that is how Lopetegui's team have performed in Spain's top flight this term, picking up 10 points to leave themselves in 12th position in the table.
Sevilla actually lost three straight league matches to Granada, Eibar and Athletic Bilbao between October 17 and October 31, but they managed to record a 1-0 win over Osasuna before the international break.
The Europa League holders have also made a positive start to their Champions League campaign, picking up seven points from three matches to sit second in Group E, level on points with Chelsea.
Los Nervionenses will be determined to make it successive league wins this weekend, but they only collected one point from their two matches with Celta during the 2019-20 La Liga campaign.
Celta, meanwhile, have only won one of their nine league matches this season, picking up seven points in total to sit 17th in the table, just one point outside of the relegation zone.
Huesca and Levante will both play before Celta take to the field for this match, meaning that the Sky Blues could be inside the relegation zone by the time that kickoff arrives.
Coudet has previously been in charge of Rosario Central, Club Tijuana, Racing Club and Internacional, but the 46-year-old does not have any European managerial experience.
The Celts have finished 17th in La Liga in each of the last two campaigns, and it does appear that it will be another tough season for a club battling to stay in the top flight.
Sevilla La Liga form: WDLLLW
Sevilla form (all competitions): DLWLWW
Celta Vigo La Liga form: LLLDLD
Sevilla possible starting lineup:
Bounou; Escudero, Kounde, Carlos, Acuna; Rakitic, Fernando, Jordan; Munir, L De Jong, Ocampos
Celta Vigo possible starting lineup:
Blanco; Mallo, Aidoo, Murillo, Olaza; Mendez, Tapia, Beltran; Nolito, Aspas, Suarez
We say: Sevilla 2-0 Celta Vigo
Sevilla have been far from their best in the league this season, while Celta could be boosted by a change of manager. The hosts will be determined to make it back-to-back victories in Spain's top flight, though, and we are finding it difficult to back anything other than a routine success for Lopetegui's team.