The two sides at the top of the Serie A table clash at Stadio Olimpico on Friday night with Roma having the chance to temporarily move five points clear of Napoli with victory over them.
Roma have won all seven of their games to start the new league season and they have also conceded just one goal in those games.
Napoli, too, are undefeated in the league and have won all three of their games away from Stadio San Paolo.
For Roma, Morgan De Sanctis will play in goal against his old side while Daniele De Rossi is expected to win a fitness battle to play.
For Napoli Christian Maggio, Juan Zuniga and Gonzalo Higuain could all return to the side for this vital clash.
Recent form
Roma: WWWWWW
Napoli: WWWDWW
Possible starting lineups
Roma: De Sanctis; Castan, Benatia, Balzaretti, Torosidis; Florenzi, Pjanic, De Rossi, Strootman; Totti, Gervinho
Napoli: Reina; Fernandez, Britos, Zuniga; Maggio, Behrami, Hamsik, Inler, Mertens; Callejon, Higuain
Sports Mole says: 2-1
Matt Domm
