The Irish face the world champions in Gelsenkirchen as big underdogs to leave with a positive result, and O'Neill, whose side beat Gibraltar 7-0 on Saturday, hints that attack may be the best form of defence.
"We are going with some confidence into the game. If we are pressed back, then okay, but if we deliberately sit in, then Germany will eventually pick you off," he told Sky Sports News.
"We want to try to attack as well. It's a game to relish. It's one where we want to go out and do something about the game, not just let the game disappear."
Kickoff tomorrow is scheduled for 7.45pm.