Rennes have struggled for form since the injury to Romain Alessandrini and their current run of six without a win has seen them drop to 10th.
PSG have been indifferent of late but have picked up in their last three games, with two wins and a draw from them.
Alessandrini is out for the rest of the season for the hosts, while they will also be without the injured Cheick Diarra.
PSG have an almost full-strength side to choose from, but Carlo Ancelotti could look to rest a few players with one eye on the return Champions League quarter-final match against Barcelona a few days after.
Possible starting lineups
Rennes: Costil; Theophile-Catherine, Kana-Biyik, Mavinga, Boye; Pajot, Feret, Pitroipa, Makoun; Diallo, Erding
PSG: Sirigu; Jallet, Alex, Thiago Silva, Maxwell; Beckham, Matuidi, Lucas Moura, Pastore; Ibrahimovic, Lavezzi
Sports Mole says: 1-2