The White and Blues have struggled for form since returning to action last month and are holding onto seventh place, while Sevilla are already assured of a top-four finish.
Villarreal's defeat to Real Sociedad on Monday ensures that Sevilla will be competing in the Champions League next season after a two-year absence.
Los Nervionenses have been in good form of late, winning four on the bounce and going 15 matches without defeat in all competitions either side of the three-month hiatus.
Finishing above Atletico Madrid in third is an attainable target for Julen Lopetegui's side given that they are level on points with Atleti with two games to play.
However, focus will no doubt be on their Europa League last-16 tie with Roma, which has been rearranged for August on neutral soil.
It is shaping up to be a season to remember for Sevilla, then, and the same is very much true for Sociedad as they are also still battling on two fronts.
As well as looking to hold off Athletic Bilbao for sixth place and the guarantee of Europa League football, the Royal will also face their Basque rivals in the Copa del Rey final.
Rather than looking behind at Athletic, though, Imanol Alguacil will no doubt be looking up at Getafe and Villarreal, with just three points separating the sides.
The 2019-20 season could have offered even more for Sociedad, however, given that they were fourth not so long ago following a run of four wins in five matches.
Having lost three of their last four home matches, though, and won just one of their last seven league encounters with Sevilla, picking up the win they need on Thursday will be a big ask.
Real Sociedad's La Liga form: LLWDLW
Sevilla's La Liga form: DDWWWW
Willian Jose has yet to register in six La Liga meetings with Sevilla - his worst run against any side in the competition - though he is likely to start alongside Mikel Oyarzabal.
Real Sociedad possible starting lineup:
Moya; Zaluda, Llorente, Normand, Monreal; Odegaard, Zubeldia, Merino; Portu, Willian Jose, Oyarzabal
Sevilla possible starting lineup:
Bounou; Navas, Kounde, Carlos, Escudero; Jordan, Fernando, Banega; Ocampos, De Jong, Munir
We say: Real Sociedad 1-1 Sevilla
There is no doubt that Sociedad have dropped off the pace since last month's restart, losing five and drawing two of their last nine matches. Sevilla have won just one of their last eight La Liga games in San Sebastian, however, so we can see this one ending all square.