The World Cup-winning Frenchman has now returned a negative coronavirus test and joined up with his teammates for training on Monday morning, so he is in line to replace Victor Chust at the back.
Zidane's defensive options are also boosted by the return of Nacho Fernandez from suspension, so Alvaro Odriozola's spot at right-back is at risk, but two more players on that side in Lucas Vazquez and Dani Carvajal are both nursing injuries.
Toni Kroos was given a complete rest against Getafe but is expected to reprise his regular role in midfield here, so Zidane could sacrifice Rodrygo after he struggled to produce the goods at the weekend.
However, Federico Valverde is in self-isolation after coming into close contact with a COVID-positive individual, while Eden Hazard was not spotted at Monday's training session, despite Zidane affirming that he was "ready" to return to action.
Real Madrid possible starting lineup:
Courtois; Nacho, Militao, Varane, Marcelo; Casemiro, Kroos, Modric; Asensio, Benzema, Vinicius Jr