Real Madrid manager Jose Mourinho has handed Diego Lopez his second debut for the club against Barcelona in the Copa del Rey, after he rejoined from Sevilla last week.
Barca, who are still under the guidance of assistant boss Jordi Roura, welcome back Gerard Pique, Andres Iniesta and Cesc Fabregas. The Catalan outfit are still without head coach Tito Vilanova, who is currently recovering from a tumor in the United States.
Real Madrid: Lopez; Essien, Varane, Carvalho, Arbeloa; Khedira, Alonso, Ozil; Callejon, Ronaldo, Benzema
Barcelona: Pinto; Alves, Pique, Puyol, Alba; Xavi, Busquets, Fabregas; Pedro, Messi, Iniesta