Another victory is imperative at the Doosan Arena in midweek if the Champions League holders are to remain on course for a place in the last 16 of the competition.
Ahead of the Group G tie in the Czech Republic, Sports Mole looks at how the European champions could line up.
Solari has inherited a side with a number of defensive absentees, as Marcelo - the scorer of three goals in three games before being struck down by injury - Carvajal, Varane and Vallejo are all still out.
Sergio Reguilon was Madrid's best player on his La Liga debut against Valladolid at the weekend and should therefore retain his place at left-back, while Nacho Fernandez will continue to provide cover alongside Sergio Ramos in the middle.
The key moment in the 2-0 win against Valladolid was provided by Vinicius Junior's deflected shot to open the scoring, and the highly-rated youngster could be rewarded with a first start since joining, while Isco and Marco Asensio are also options on the left of Madrid's expected three front.