Reading will be hoping to put an end to their recent poor form, which has seen them lose eight of their last nine league games. Nigel Adkins's side were beaten 2-1 by Norwich City last weekend to remain bottom of the league.
QPR, who have lost four of their last five league matches, are joint bottom of the table with 24 points, 10 adrift of safety with four games remaining.
Reading boss Adkins will be without several first-team players for the match, with Adam Federici and Jimmy Kebe to miss out through injury. Hope Akpan, who is nearing a return to action following an ankle injury, may be named on the bench.
Possible starting lineups
Reading: McCarthy; Gunter, Mariappa, Morrison, Kelly; Karacan, Guthrie, McAnuff, McCleary; Pogrebnyak, Hunt
QPR: Green; Bosingwa, Samba, Hill, Ben Haim; Hoilett, Derry, M'Bia, Townsend, Taarabt; Remy
Sports Mole says: 2-1