Visitors Charlton have lost three of their last four and go into tomorrow night's match on the back of a 1-0 home defeat to Ipswich Town.
Despite the loss, boss Chris Powell is likely to start the same XI. First-choice goalkeeper Ben Hamer may return from a knee injury, but if he is not fit, then Ben Alnwick will continue between the sticks.
It is five years since these two were in the same division and that term there were 10 goals in the two games.
Possible starting lineups
Reading: McCarthy; Cummings, Pearce, Gorkss, Kelly; Williams, Guthrie Obita; McCleary, Pogrebnyak, Robson-Kanu
Charlton: Alnwick; Wilson, Morrison, Dervite, Wiggins; Stewart, Stephens, Jackson, Cousins; Kermorgant, Church
Sports Mole says: 3-1