The R's have not won on their travels since November, but Hughes remains hopeful that the poor run can be ended on Sunday.
"We've got to try to address our away form in the final two fixtures on the road. If we can be disciplined against Chelsea then we could get a positive result. It's a great London derby for the fans," Hughes told Sky Sports News.
"It would be massive if we could get something positive from the trip to Stamford Bridge and then come back to Loftus Road for a huge game against Stoke."
QPR currently sit 16th in the Premier League table.