Ferencvaros vs. Young Boys (Tuesday, 8.00pm)
Meanwhile, the visitors managed to claim a first-leg advantage with 10 men last week and will now seek to finish the job en route to the group stage.
We say: Ferencvaros 1-2 Young Boys (Young Boys win 5-3 on aggregate)
The first leg of this playoff tie was goals galore, and given Young Boys' affinity for attacking, it would be a surprise to see the visitors sit back in a bid to weather the Ferencvaros storm.
Both teams once again have fresh suspension concerns to work around, and another closely-fought affair should be in order here, but we are tipping the visitors' penchant for goals to carry them over the line and into the group stages.
Ludogorets vs. Malmo (Tuesday, 8.00pm)
Goals from Veljko Birmancevic and Jo Berget put the Swedish side in control during the first leg, and Jon Dahl Tomasson's side now travel to Bulgaria aiming to finish the job.
We say: Ludogorets Razgrad 2-1 Malmo (Malmo win 3-2 on aggregate)
The return of key attacking figure Despodov will undoubtedly give the hosts a greater attacking edge, while their visitors are unlikely to have the wise old head Moisander marshalling the defence.
Ludogorets have only been marching to victories on home soil and that is unlikely to change here, but Malmo should keep the encounter close and scrape through to the promised land.
PSV vs. Benfica (Tuesday, 8.00pm)
Benfica ran out 2-1 winners in the first leg on August 18, with Rafa Silva and Julian Weigl scoring the goals for Jorge Jesus's side, leaving PSV with work to do in the second leg in Eindhoven.
We say: PSV Eindhoven 1-1 Benfica (Benfica win 3-2 on aggregate)
This is an incredibly difficult match to call, and it would not be a surprise to see it go all the way to a penalty shootout. PSV will believe that they can harm Benfica in the final third, but the Portuguese outfit are in excellent form, and we fancy the visitors to claim a 1-1 draw in order to win 3-2 on aggregate.