Jonathan Woodgate's side have enjoyed an upturn in form recently, which has seen them keep their sixth spot in the Championship table, but their playoff place remains under major threat from the chasing pack.
Preston have struggled for form recently, picking up just two victories from their last nine Championship outings.
Most recently, Alex Neil's side fell to a 2-1 defeat away at Millwall on Tuesday night, when Ched Evans gave the Lancashire side the lead before a Scott Malone finish and a late Mason Bennett goal won the game for Millwall.
Neil's men now sit 14th due to their recent poor form and drop down the table, as they look set for a mid-table finish.
Worryingly for the Scottish manager, his side have one of the worst home records in the Championship this season, picking up just 18 points from their 17 games at Deepdale, losing nine of those matches.
That could be made even worse on Saturday, as they welcome a Bournemouth side with renewed confidence following consecutive victories.
Last time out, the Cherries recorded a crucial 2-1 victory away at a resurgent Bristol City side.
Centre-back Cameron Carter-Vickers then headed a corner in at the back post in the final few minutes to seal all three points for Bournemouth.
Before that, they secured an impressive 1-0 win over Watford at the Vitality Stadium, as Arnaut Danjuma netted the only goal of the match before the game ended in a large melee which saw Joao Pedro and Jack Wilshere sent off.
Since his appointment, Woodgate has failed to bring about a consistent run of results, however their last two wins have provided a platform to build on as they aim to win promotion back to the Premier League at the first time of asking.
Preston North End Championship form: WLLDWL
Bournemouth Championship form: DWLLWW
Sean Maguire remains a doubt for this game, despite making major progress following a recent injury, as Alex Neil is unlikely to risk the Irish attacker by throwing him back into action too quickly.
Meanwhile, club captain Alan Browne is also a doubt after missing the Millwall defeat with a minor injury.
Welsh striker Ched Evans will come into this game with some confidence, having scored in both of his last two games.
Bournemouth will remain without David Brooks, who has been absent from the squad for their last four games.
However, they will be boosted by the return of Jack Wilshere, who served his suspension last time out for the red card shown against Watford.
Ben Pearson could feature against his former club on Saturday, after he moved from Preston to Bournemouth in the January transfer window.
Preston North End possible starting lineup:
Iversen; Van den Bergh, Storey, Hughes, Cunningham; Molumby, Whiteman; Barkhuizen, Johnson, Gordon; Evans
Bournemouth possible starting lineup:
Begovic; Smith, Carter-Vickers, S Cook, Kelly; L Cook, Lerma, Billing; Danjuma, Solanke, Stanislas
We say: Preston North End 0-2 Bournemouth
We expect the Cherries to secure a third consecutive win on Saturday as they look to strengthen their bid for a playoff place.
Preston have majorly struggled with injuries recently, and their weakened side should be outclassed by Woodgate's men, who come in with plenty of renewed confidence.