Latvia are still looking for their first win of the campaign but they will take belief from their recent results against Czech Republic and Ukraine.
Latvia have not tasted success in six outings, but they head into this encounter in front of their home fans with plenty of confidence flowing within their ranks.
The 6-0 reverse in the Netherlands will inevitably be at the back of their minds, but since then, they have recorded 1-1 draws with both Czech Republic and Ukraine.
Both results are big achievements given their current world ranking of 85, and while they are underdogs against the Dutch, they won't be overawed by playing one of the giants of international football.
Twenty-year-old striker Valerijs Sabala could be key to their hopes, with the FK Baumit Jablone frontman having scored three of his side's last five goals.
Coach Marian Pahars will also be calling upon the likes of experienced duo Kaspars Gorkks and Aleksejs Visnakovs to help the younger members of the squad cope with the greater expectation of the team after their recent improvements.
Recent form: DLDLD
Recent form (all competitions): DLDLDD
Oranje have suffered five defeats in their last nine games, including setbacks to Czech Republic and Iceland, and although they overcame Spain in March, they were brought back to earth last Friday.
Netherlands looked on course to stretch their unbeaten run to four games when they opened up a 3-1 advantage against USA but after they conceded three goals during the closing stages, morale is low ahead of the match in Riga.
The result led to Hiddink criticising his team, and with Netherlands sitting well adrift of second-placed Iceland, they desperately need three points to not only boost their campaign, but potentially keep Hiddink in a job too.
In Robin van Persie, Klaas-Jan Huntelaar and Wesley Sneijder, Hiddink has a trio with 118 international goals between them, but their promising crop of young talent also need to step up in a bid to restore the team to its former glory.
Recent form: LWLWD
Recent form (all competitions): LLWDWL
After the setback to the USA, Hiddink is unlikely to keep with the same team, although the majority of his attacking players should be safe from demotion to the bench.
However, defender Stefan de Vrij and midfielder Sneijder should find themselves drafted back into the starting lineup.
As for Latvia, Pahars is without midfielder Olegs Laizans, who was left out of the squad because of injury.
Latvia possible starting lineup:
Vanins, Gorkss, Dubra, Maksimenko, Freimanis, Tarasovs, Lazdins, Zjuzins, Visņakovs, Rakels, Sabala
Netherlands possible starting lineup:
Cillessen; Janmaat, Blind, De Vrij, Martins Indi; Clasie, Wijnaldum, Sneijder, Memphis; Van Persie, Huntelaar
Head To Head
The two teams have only ever met twice on the international stage, with the first fixture at Euro 2004 ending in a 3-0 win for the Netherlands.
We say: Latvia 1-4 Netherlands
There is sure to be a bit of tension within the Netherlands camp ahead of this game, but their big-match experience should pull them through. Latvia have the potential to cause them a few problems but the firepower of the Dutch should be too hot to handle for the home side.