Rafael Benitez's job was thought to be under threat earlier this season, but the former Liverpool boss has guided an unbeaten six-match record in Italy's top flight.
The seventh-placed side were close to taking nothing away from their clash against Atalanta BC on Wednesday evening until Gonzalo Higuain struck in the 86th minute to equalise.
Napoli had the chance to win the game when they were awarded a penalty in stoppage time, but the former Real Madrid man had his effort saved.
Despite losing to the Old Lady earlier this month, Roma are equal on 22 points with their rivals, and both clubs have plus 12 goals, but Garcia's side arguably have a tougher fixture against Napoli while Juve face Empoli, who are lingering above the relegation zone.
For the home side, Higuain and Jose Callejon are expected to provide the attacking threat on Saturday.
Possible starting lineups
Napoli: Rafael; Ghoulam, Koulibaly, Albiol, Maggio; Mertens, Hamsik, Inler, David Lopez; Callejon, Higuain
Roma: Skorupski; Torosidis, Manolas, Astori, Cole; Pjanic, De Rossi, Keita; Iturbe, Destro, Gervinho
Sports Mole says: 2-2