Both teams will be looking to build on victories last time out, with the hosts beating Maritimo 2-0 while Rio Ave defeated Farense by the same scoreline last Sunday.
Moreirense returned to winning ways in their last game, defeating Maritimo 2-0 away from home thanks to a Filipe Soares brace.
That stopped a winless run from growing for Os Verdes e Brancos, having previously gone three league games without a victory.
That run also included a disappointing 1-0 loss to Boavista, with Angel Gomes netting the only goal of the game to seal all three points for the side who sat at the foot of the table at the time.
Seabra will be hoping that his side can put that run behind them now, as they look to record consecutive wins in the top flight in order to maintain their seventh spot.
However, Rio Ave will also be in search of a second straight victory, as a win would move them just one point behind Sunday's opponents.
Miguel Cardoso's side also returned to winning ways last time out, defeating a resurgent Farense side 2-0 at home.
As a result of that win, Cardoso's men moved back up to ninth spot in the top flight, sitting just one point behind eighth-placed Santa Clara, and four points behind Moreirense.
That was a big relief for the Rioavistas, as they sat just three points above the relegation zone before Sunday's victory, with that gap now standing at six points.
Cardoso will now focus his attention back up the league, as his side look to move within a point of Moreirense and continue their climb back up the table.
Moreirense will be without right-back Anthony D'Alberto, who will serve a suspension after he picked up his fifth yellow card of the season last time out.
However, they did recently welcome Felipe Pires back to action, with the winger coming off the bench in their last two games after a spell on the sidelines.
Young Manchester City loanee Nahuel Ferraresi has impressed in defence recently, cementing himself in the starting lineup.
Their line will be led by Rafael Martins and Filipe Soares, with each player netting a brace in one of their last two games.
Key forward Gelson Dala has struggled for goals this campaign, netting just two from his 20 league appearances.
Moreirense possible starting lineup:
Pasinato; Ba, Ferraresi, Rosic, Conte; Yan, Pacheco, A Soares, Walterson; Martins, F Soares
Rio Ave possible starting lineup:
Kieszek; Costinha, Santos, Borevkovic, Savio; Augusto, Pele; Mane, Geraldes, Camacho; Dala
We say: Moreirense 2-1 Rio Ave
With the visitors remaining weakened by injuries, we see Moreirense just edging this encounter at their home ground.
With Rafael Martins and Filipe Soares both coming in with plenty of confidence, Seabra's men should be able to find goals against a makeshift Rio Ave back line, firing them to an important victory.