Mowbray's former assistant Mark Venus will take temporary charge for the match at the Riverside Stadium.
Meanwhile, 17th-placed Doncaster are also in need of the points following two defeats in their last two fixtures.
Doncaster are likely to be without captain Rob Jones, who is currently suffering with an arm injury.
Boro: Steele; Richardson, Friend, Leadbitter, Hines; Gibson, Butterfield, Whitehead, Jutkiewicz; Kamara, Adomah
Doncaster: Turnbull; Quinn, Wabara, Keegan, Khumalo; Bennett, Coppinger, Furman; Brown, Wellens, Duffy
Sports Mole says: 1-1