The Blues are still unbeaten since Thomas Tuchel's arrival at the club but were held to a 1-1 draw by Southampton in the league last weekend, which has left them in fifth position in the table, two points behind fourth-placed West Ham United, who face leaders Manchester City on Saturday.
The capital side will enter this weekend's contest off the back of a positive result, though, having beaten Atletico Madrid 1-0 in the first leg of their last-16 Champions League clash on Tuesday night.
Here, Sports Mole looks at how the home side could line up at Stamford Bridge.
Out: Thiago Silva (muscle)
Chelsea had hoped that Thiago Silva would recover from a muscular problem in time for Sunday's contest, but Tuchel revealed during his pre-match press conference that the Brazilian is still unavailable.
As a result, Andreas Christensen is set to continue in the middle of the defence, and the Blues are otherwise in excellent shape in terms of injuries, meaning that head coach Tuchel has a number of decisions to make.
Watch the Sports Mole Football Shorts prediction for this game below: