Manchester United head coach Michael Carrick is likely to hand a debut to Andrey Santos in Saturday's pre-season friendly with Championship outfit Wrexham.
Santos - a £50m arrival from Chelsea - is in line to feature in the middle of the Red Devils midfield, but Karl Darlow will not make his debut this weekend, with the goalkeeper recovering from a procedure that he had at the end of last season.
First-team stars Leny Yoro, Patrick Dorgu, Ayden Heaven, Harry Maguire, Luke Shaw, Mason Mount, Bryan Mbeumo and Joshua Zirkzee are all available, but Benjamin Sesko is still dealing with a shin issue and is not in the squad.
Harry Amass, Shea Lacey, Chido Obi, Jack Fletcher and Toby Collyer are among the youngsters who could be involved, having been included in the travelling squad.
However, Lisandro Martinez (Argentina) Matheus Cunha (Brazil), Diogo Dalot (Portugal), Bruno Fernandes (Portugal), Amad Diallo (Ivory Coast), Altay Bayindir (Turkey), Kobbie Mainoo (England), Senne Lammens (Belgium), Noussair Mazraoui (Morocco) and Marcus Rashford (England) are all absent due to World Cup commitments, either ongoing or previous.
Youri Tielemans is another new signing at Old Trafford, but the midfielder represented Belgium at the 2026 World Cup and is not yet ready to join up with the squad.
Matthijs de Ligt and Manuel Ugarte are long-term absentees, meanwhile, due to injury issues.
Manchester United possible starting lineup:
Darlow; Yoro, Maguire, Heaven, Shaw; Santos, Collyer; Lacey, Mount, Dorgu; Mbeumo
Vote in the Sports Mole World Cup 2026 Readers’ Awards!
Cast your votes for the 2026 World Cup awards; from player of the tournament and breakout star, to best attacker and biggest disappointment.
Voting will be open until 11pm UK time on Monday, July 20, and the winners announced on Tuesday, July 21!