The Dutchman missed United's shock defeat to Swansea City in Saturday's curtain raiser after being granted an extended holiday following the World Cup.
Van Persie has been training with the Red Devils for the past two-and-a-half weeks, and the 31-year-old took to Twitter to hint that he is ready for his first game of the season.
Good training session done this morning. Looking forward to sunday! pic.twitter.com/kbeZTx7TOU— Robin van Persie (@Persie_Official) August 21, 2014
Sunday's clash at the Stadium of Light is scheduled to kick off at 4pm.