Everton vs. Chelsea (Saturday, 12.30pm)
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Chelsea make the trip to Goodison Park to face Everton having strengthened their grip of fourth position with a 2-1 victory over Aston Villa.
Meanwhile, with Wednesday night's 5-2 defeat to Liverpool seeing the club drop into the relegation zone, Everton have decided to part ways with Marco Silva, replacing the Portuguese with Duncan Ferguson on a caretaker basis.
We say: Everton 2-2 Chelsea
Chelsea supporters have gotten used to their team being involved in entertaining matches this season, and we see no reason why it should be any different this weekend. However, while the visitors will feel that they should be taking advantage of Everton's current situation, we are backing the Toffees to claim a share of the spoils.
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> How Chelsea could line up against Everton
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Bournemouth vs. Liverpool (Saturday, 3pm)
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Bournemouth will be the latest team to attempt to stop the Liverpool juggernaut when Jurgen Klopp's runaway Premier League leaders visit the Vitality Stadium on Saturday afternoon.
The Reds have dropped just two points from their opening 15 games to build a commanding eight-point lead at the top, and will be expected to chalk up yet another victory against a Cherries side on a dreadful run of form.
We say: Bournemouth 1-4 Liverpool
This match pits a team which cannot stop losing at the moment against a team which cannot stop winning - surely there can be only one outcome. Liverpool have enjoyed their December trips to Dean Court in the past two years, and with some big names returning after being rested they look well placed to do so again.
For all of their success, Klopp's side cannot seem to keep a clean sheet at the moment and so we can see Bournemouth ending their four-game drought against Liverpool, but that may be the only thing they have to cheer on Saturday.
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> How Liverpool could line up against Bournemouth
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Tottenham vs. Burnley (Saturday, 3pm)
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Tottenham Hotspur and Burnley will be looking to recover from poor results during the week when the two sides meet in the Premier League on Saturday.
Jose Mourinho suffered his first defeat as Spurs boss at former club Manchester United on Wednesday, while Burnley were comfortably beaten by Manchester City the day before.
We say: Tottenham Hotspur 1-0 Burnley
Spurs will be made to work hard for all three points against a militantly organised Burnley side, but following the defeat at Old Trafford, Mourinho's men will be desperate to stamp their authority and produce a professional performance, which should be enough yield a narrow victory.
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> How Spurs could line up against Burnley
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Watford vs. Crystal Palace (Saturday, 3pm)
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Watford meet Crystal Palace at Vicarage Road in the Premier League on Saturday with the Hornets desperate for three points.
The home side are rock bottom in the table and recently sacked their second manager of the season, while Palace are enjoying a wonderful start to the 2019-20 campaign under Roy Hodgson.
We say: Watford 1-2 Crystal Palace
In front of their own supporters and already in survival mode, Watford will no doubt give a strong account of themselves against Palace and look likely to nick a goal.
However, over 90 minutes, the demons that have been plaguing this Watford side will shine through, which the likes of Zaha and Andros Townsend will gladly take advantage of.
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Man City vs. Man Utd (Saturday, 5.30pm)
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Manchester City welcome Manchester United to the Etihad Stadium on Saturday for the 179th edition of the Manchester derby as both sides look to build on midweek wins.
The champions cruised to a 4-1 victory over Burnley at Turf Moor to return to winning ways, whereas United beat Tottenham Hotspur 2-1 on former manager Jose Mourinho's first return to Old Trafford.
We say: Man City 3-1 Man Utd
United have an admirable record at the home of their local rivals in recent years, but their away form in general has suffered a nosedive since then whereas City have been imperious at the Etihad Stadium. There is always an added element of uncertainty when predicting derby matches, but Man City are comfortably the stronger of the two teams and should have enough to see off their neighbours.
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> How Man City could line up against Man Utd
> How Man Utd could line up against Man City
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> Combined XI: Man City vs. Man Utd
Aston Villa vs. Leicester (Sunday, 2pm)
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Leicester City will be looking for their eighth straight win in the Premier League when they travel to Villa Park to face Aston Villa on Sunday afternoon.
A stunning run of form has seen the Foxes rise into second position in the table, while Villa occupy 16th spot having collected 15 points from their 16 league outings during the 2019-20 campaign.
We say: Aston Villa 1-1 Leicester City
This is a tough game for Leicester when taking everything into consideration. The Foxes are certainly capable of picking up all three points, but we fancy Villa to secure a share of the spoils.
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Newcastle vs. Southampton (Sunday, 2pm)
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Two teams in good form will lock horns at St James' Park on Sunday afternoon as Newcastle United welcome Southampton for what should be a fascinating encounter.
Newcastle have won three of their last five in the Premier League to rise into 11th position in the table, while Southampton are out of the relegation zone following back-to-back victories.
We say: Newcastle United 2-1 Southampton
Both teams will enter the match full of confidence due to their recent form but when taking everything into consideration, we just fancy Newcastle to record a narrow win in front of their own supporters.
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Norwich vs. Sheffield United (Sunday, 2pm)
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Both Norwich City and Sheffield United will be looking to bounce back from midweek Premier League defeats when they lock horns at Carrow Road on Sunday afternoon.
Norwich's 2-1 loss at Southampton has left them down in 19th spot in the table, while Sheffield United dropped to ninth following their 2-0 home defeat to Newcastle United.
We say: Norwich City 1-1 Sheffield United
Both teams will believe that they can cause problems in the final third of the field, and we are finding it difficult to separate them. Sheffield United are just struggling for a win at the moment, while Norwich have not been victorious on home soil since overcoming Manchester City in the middle of September.
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Brighton vs. Wolves (Sunday, 4.30pm)
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Wolverhampton Wanderers will continue their pursuit of fourth-placed Chelsea when they travel to Brighton & Hove Albion in the Premier League on Sunday afternoon.
Nuno Espirito Santo's side are currently fifth in the table with 23 points, while Brighton's 2-1 win at Arsenal on Thursday night saw them move into 13th spot ahead of this weekend's fixtures.
We say: Brighton & Hove Albion 2-2 Wolverhampton Wanderers
Both teams will enter the match off the back of positive results during the week, and it should be an open and entertaining contest on Sunday afternoon. We fancy a score draw at the Amex Stadium, which would not be the worst result in the world for either side.
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West Ham vs. Arsenal (Monday, 8pm)
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Arsenal's search for an overdue win takes them to the London Stadium next as they face West Ham United looking to end their worst run of form for 42 years.
The Gunners are now nine games without a victory across all competitions following Thursday night's home defeat at the hands of Brighton & Hove Albion, but take on a West Ham side with only one win in 10 themselves.
We say: West Ham 2-2 Arsenal
This is a battle between two woefully out-of-form teams, pitting a poor home record against a poor away one. It is difficult to back either side to pick up all three points on current form, particularly with the defences shipping goals for fun at the moment. We are going for a score draw.
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> How Arsenal could line up against West Ham
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