Ole Gunnar Solskjaer will want to rest a few key players for Manchester United's meeting with Kazakhstani champions Astana in the Europa League on Thursday.
The Norwegian already has a burgeoning injury list and will not want to subject certain players to a trip to an away venue that is closer to Hong Kong than Manchester.
Moreover, there is no pressure on United, whose pair of victories over Partizan prior to the international break cemented their place in the knockout phases.
Here, Sports Mole rounds up United's latest injury and suspension news ahead of this fixture.
Eric Bailly
Status: Out Type of injury: Knee Possible return date: December 15 (vs. Everton)
Bailly continues to recover from a knee ligament injury sustained over pre-season but has recently made a return to light training ahead of completing a return next month.
Paul Pogba
Status: Out Type of injury: Foot Possible return date: December 7 (vs. Manchester City)
The Frenchman's foot problem, initially sustained in August, continues to keep him stuck on the sidelines, with Solskjaer recently confirming that he hopes to have him back by early December.
Luke Shaw
Status: Major doubt Type of injury: Thigh Possible return date: November 28 (vs. Astana)
Sidelined since August, Shaw has recently made a return to training after recovering from a thigh problem, although the Englishman still lacks match fitness.
Nemanja Matic
Status: Major doubt Type of injury: Other Possible return date: November 28 (vs. Astana)
Much like Shaw, Matic has recovered from an unspecified injury but continues to lack appropriate match fitness, with Solskjaer unlikely to risk him on Thursday.
Diogo Dalot
Status: Out Type of injury: Groin Possible return date: December 15 (vs. Everton)
The youngster has been plagued by a groin injury since the start of the season and remains some way away from making a return to full fitness.
Timothy Fosu-Mensah
Status: Out Type of injury: Knee Possible return date: Unknown
One of United's long-term absentees, Fosu-Mensah is back in light training after several months out with knee ligament damage, and it remains to be seen as to when he will be ready for a return to the pitch.
Scott McTominay
Status: Out Type of injury: Ankle Possible return date: December 7 (vs. Manchester City)
Solskjaer confirmed that an ankle injury sustained by McTominay prior to the November international break would keep the midfielder out for "a couple of weeks", meaning that the Manchester derby would be the earliest he could return.
Marcos Rojo
Status: Out Type of injury: Muscle Possible return date: December 7 (vs. Manchester City)
Solskjaer noted in a press conference on Friday that Rojo had picked up a muscular injury over the international break that will keep him sidelined until early December.
MANCHESTER UNITED'S SUSPENSION LIST
United have no players who are suspended ahead of this fixture.