David Moyes's side currently top the table after taking four points from their opening two matches.
However, there is sure to be a feeling of unease around the 'Theatre of Dreams' considering the team's shaky form in the Premier League.
United dropped yet more points on Saturday as they were held to a 1-1 draw by Southampton at home.
Sociedad arrive in Manchester on the back of two consecutive defeats in Europe, but they are likely to be buoyed by a 2-1 win over Valencia in La Liga at the weekend.
Man Utd: LWLDWD
Possible starting lineups
Man Utd: De Gea; Rafael, Vidic, Ferdinand, Evra; Nani, Carrick, Fellaini, Valencia; Rooney, Van Persie
Sociedad: Bravo; C Martinez, Gonzalez, I Martinez, De La Bella; Vela, Bergara, Pardo, Griezmann; Zurutuza; Agirretxe
Sports Mole says: 2-0