The 27-year-old has not featured since August because of a knee injury, but Ferguson has revealed that the England international is ready to return.
"We've got Ashley Young back and he'll be involved tomorrow. We've got Nani, Antonio Valencia, Ryan Giggs - plenty of wide players. I have an issue in terms of picking the team. Hopefully I get it right," he told reporters.
"Shinji Kagawa didn't play on Saturday so he can prepare for tomorrow. Also, Stoke's a different team to any other side he's played. But mainly it was to give him a rest before tomorrow."
United have won both of their Champions League group clashes thus far.