City boss Pep Guardiola gave the defender an immediate debut against West Bromwich Albion in midweek, but the former Athletic Bilbao player is only among the replacements for the short trip to Clarets.
Guardiola has opted to only name six substitutes - rather than promote a youth team prospect - with Fabian Delph, David Silva, Benjamin Mendy, Leroy Sane, Gabriel Jesus and Phil Foden all on the sidelines.
Burnley: Pope; Bardsley, Long, Mee, Taylor; Cork, Hendrick; Lennon, Barnes, Gudmundsson; Vokes
Subs: Lindegaard, Lowton, Nkoudou, Arfield, O'Neil, Wells, Westwood
Manchester City: Ederson; Walker, Danilo, Kompany, Otamendi; Fernandinho, Gundogan, De Bruyne, Bernardo, Sterling; Aguero
Subs: Bravo, Laporte, Adarabioyo, Zinchenko, Yaya Toure, Diaz
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