The reigning English champions currently sit third in the Premier League table, with Chelsea topping the league by just one extra point.
Meanwhile, the Hammers can edge closer to the top five if they cause an upset to the champions on their home ground of Upton Park on Saturday.
West Ham boss Sam Allardyce is expected to rely on Andy Carroll as the side's main goal threat, with Kevin Nolan controlling the midfield, while City boss Roberto Mancini could welcome back David Silva, who has been dealing with a hamstring injury.
West Ham: DWLWL
Man City: DWWWW
West Ham: Jaaskelainen; Tomkins, Collins, Reid, McCartney; Jarvis, Noble, Nolan, Diame, Benayoun; Carroll
Man City: Hart; Zabaleta, Nastasic, Kompany, Clichy; Nasri, Toure, Barry, Silva; Tevez, Aguero
Sports Mole says: 1-2