The 26-year-old has enjoyed a fruitful season at club level, scoring 19 goals and claiming nine assists en route to fourth place in the Premier League table and the Champions League final.
The 27-year-old broke his thighbone and jaw in a car crash on London's M4 in 2016 and was sidelined for over a year.
Although Souare returned to the Senegal squad in March, he only made only four substitute appearances for Palace during the 2017-18 season.
Senegal are in Group H of the 2018 World Cup alongside Colombia, Japan and Poland.
Goalkeepers: Abdoulaye Diallo (Stade Rennes), Alfred Gomis (SPAL), Khadim Ndiaye (Horoya)
Defenders: Lamine Gassama (Alanyaspor), Saliou Ciss (Valenciennes), Kalidou Koulibaly (Napoli), Kara Mbodii (Anderlecht), Youssouf Sabaly (Bordeaux), Salif Sane (Hannover 96), Moussa Wague (Eupen)
Midfielders: Idrissa Gueye (Everton), Cheikhou Kouyate (West Ham United), Alfred N'Diaye (Wolverhampton Wanderers), Badou Ndiaye (Stoke City), Cheikh N'Doye (Birmingham City), Ismaila Sarr (Stade Rennes)
Forwards: Keita Balde (Monaco), Mame Biram Diouf (Stoke City), Moussa Konate (Amiens), Sadio Mane (Liverpool), Mbaye Niang (Torino), Diafra Sakho (Stade Rennes), Moussa Sow (Bursaspor)