Only a win will do for the visitors in terms of their top-four hopes, as they look to take full advantage of Alisson Becker's iconic winner against West Bromwich Albion last time out.
Here, Sports Mole rounds up the latest team news for both sides.
Sports Mole's predicted XI: Peacock-Farrell; Lowton, Tarkowski, Mee, Taylor; Brownhill, Cork, Westwood, McNeil; Wood, Barnes
Out: Jordan Henderson (groin), Joel Matip (ankle), Joe Gomez (knee), Virgil van Dijk (knee), Ozan Kabak (muscle), Ben Davies (muscle), Diogo Jota (fott)
Doubtful: Alex Oxlade-Chamberlain (illness), Naby Keita (muscle), James Milner (knock)
Sports Mole's predicted XI: Alisson; Alexander-Arnold, R Williams, Phillips, Robertson; Thiago, Fabinho, Wijnaldum; Salah, Firmino, Mane
Watch the Sports Mole Football Shorts prediction for this game below: