In all, Jurgen Klopp makes four changes from the side that were humiliated by a 5-0 scoreline at Manchester City a week ago following their midweek exertions in the Champions League, which saw them held to a 2-2 draw by Sevilla.
Coutinho returns to the starting XI having struggled with a back injury since the start of the season and a transfer window which saw him heavily pursued by Spanish giants Barcelona.
The Brazilian is expected to be eased back into action in a midfield role this afternoon alongside Emre Can and the returning James Milner, with skipper Jordan Henderson and Georginio Wijnaldum starting on the bench after their exertions in midweek.
Trent Alexander-Arnold and Ragnar Klavan are back in the back four, having been dropped in the Champions League, with Joel Matip keeping his place and Andrew Robertson coming in at left-back for Alberto Moreno.
For the visitors, Sean Dyche makes two changes to the side that claimed a narrow win over Crystal Palace last weekend, opting to play with just one man up front.
Liverpool: Mignolet; Alexander-Arnold, Matip, Klavan, Robertson; Milner, Can, Coutinho; Salah, Firmino, Sturridge
Subs: Karius, Wijnaldum, Lovren, Henderson, Moreno, Oxlade-Chamberlain, Solanke
Burnley: Pope; Lowton, Tarkowski, Mee, Ward; Gudmundsson, Cork, Arfield, Defour, Brady; Wood
Subs: Walters, Vokes, Westwood, Long, Bardsley, Barnes, Legzdins
Keep up with every twist and turn at Anfield this afternoon with Sports Mole's live text commentary here.