The England international was named on the bench for Saturday's 1-0 defeat to Aston Villa, though he came on during the second half as the Reds tried to turn the game around.
Sterling's inclusion represents the only change for the Reds, with summer signing Lazar Markovic currently suspended from European competition.
Liverpool: Mignolet; Manquillo, Moreno, Lovren, Sakho; Gerrard, Henderson; Coutinho, Sterling, Lallana; Balotelli
Subs: Jones, Enrique, Toure, Lucas, Suso, Borini, Lambert
Ludogorets: Borjan; Alek, Minev, Moti, Junior Caicara; Anicet Abel, Dyakov, Marcelinho, Aleksan; Bezjak, Misidjan
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