It had been suggested that Klopp could tweak his team following Saturday's 3-3 draw against Watford in the Premier League, but the same XI will take to the field as Sadio Mane and Mohamed Salah are selected alongside Roberto Firmino in the final third.
There is also a spot in the home side's starting XI for former Leicester City attacker Andrej Kramaric.
Hoffenheim: Baumann; Zuber, Hubner, Bicakcic, Vogt, Kaderabek; Gnabry, Demirbay, Rupp, Kramaric; Wagner
Subs: Kobel, Nordtveit, Toljan, Amiri, Uth, Szalai, Geiger
Liverpool: Mignolet; Alexander-Arnold, Lovren, Matip, Moreno; Henderson, Can, Wijnaldum; Salah, Firmino, Mane
Subs: Karius, Klavan, Gomez, Milner, Grujic, Solanke, Origi
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