The English rivals were pitted together in Friday morning's draw in Nyon, setting up a two-legged affair next month - beginning with a match at Anfield on April 4.
Rodgers is excited by the prospect of seeing two of the Premier League's heavyweight sides lock horns, and believes that it should take star billing ahead of a repeat of last year's final in Real Madrid vs. Juventus.
"It's brilliant. Two fantastic teams, it's going to be a special occasion," he told reporters. "Obviously the first game is at Anfield so Liverpool will look to make a good start in the tie there. It's a fascinating game, it should be brilliant.
"It's just a shame that both got drawn together at this stage; it would have been nice for them to have been split up, to be honest, because they're both two very, very good sides. I think it's probably the tie of the round."
Barcelona will take on Roma for a place in the final four, meanwhile, and Bayern Munich were drawn alongside Sevilla.