These two clubs have had contrasting fortunes in the Championship so far this campaign.
Both were tipped to battle it out for promotion at the start of the season, but ahead of Thursday's meeting, only Leicester City have lived up to that billing.
Nigel Pearson's team are currently second in the table and boast one of the best home records in the division. Only two teams - Crystal Palace and leaders Cardiff City - have left the King Power Stadium with maximum points.
In contrast, Wolves have only won five times on the road all season - the last of which was achieved at Blackpool back in December.
They will be without Roger Johnson for the encounter because of suspension, while there are question marks over Sylvan Ebanks-Blake's future with the club. By the time this match comes around, reports have claimed that he could be a Palace player.
Meanwhile, hosting Leicester are expected to recall Chris Wood, who started the weekend's match against Huddersfield on the bench.
Possible starting lineups:
Leicester: Schmeichel; De Laet, Morgan, Keane, Konchesky; Marshall, Drinkwater, King, Dyer; Nugent, Wood
Wolves: Ikeme; Zubar, Foley, Ward, Berra; Peszko, Davis, Henry, Sako; Ebanks-Blake, Doyle
Sports Mole says: 2-1