Leeds will be looking to bounce back from their 2-1 loss at Fulham on Saturday afternoon, while Preston will enter the match off the back of a goalless draw at Cardiff City.
There is no question that Leeds would have been disappointed by their 2-1 loss at Fulham on Saturday, but Marcelo Bielsa's side are still in a strong position at the mid-point of the 2019-20 campaign.
A total of 47 points from 23 matches has left them second in the table, just three points behind leaders West Bromwich Albion and eight clear of third-placed Sheffield Wednesday.
The Leeds supporters will not be getting too ahead of themselves, but it does appear that the Whites are in a strong position to earn automatic promotion come the end of the season.
Only West Brom (1) have lost fewer league games than Leeds (4) this term, while no side has won more (14). They have won six of their last seven Championship matches in front of their own supporters, although they did draw 3-3 against Cardiff City in their last clash at Elland Road.
The former Champions League club have also won three of their last four home league matches against Preston, not conceding a single goal in the process.
Preston have won just one of their last 10 league games against Leeds, but the visitors will enter this match off the back of an impressive run, taking seven points from their last three Championship matches.
Indeed, back-to-back wins over Fulham and Luton Town were followed by a goalless draw at Cardiff on Saturday. A return of 38 points has left them fifth in the table, nine points off their opponents on Thursday.
There are just four points between 10th-placed Nottingham Forest and Fulham in fourth, though, which is an indication of the type of season that it has been thus far in England's second tier.
Daniel Johnson has been Preston's main source of goals in the Championship this season with eight, although a number of players have chipped in due to the lack of a regular goalscorer at centre-forward.
Leeds United Championship form: WWWWDL
Preston Championship form form: LLLWWD
As for Preston, Joe Rafferty and Darnell Fisher are still suspended, but club captain Tom Clarke came through the clash with Cardiff following a long spell on the sidelines and should retain his spot.
There are not expected to be many changes from the side that lined up against Cardiff, meaning that Tom Barkhuizen should again feature in the final third.
Leeds possible starting lineup:
Casilla; Ayling, White, Cooper, Dallas; Phillips; Costa, Klich, Shackleton, Harrison; Bamford
Preston possible starting lineup:
Rudd; Clarke, Bauer, Huntington, Hughes; Gallagher, Pearson; Bodin, Browne, Maguire; Barkhuizen
We say: Leeds 1-0 Preston
The Leeds fans will be expecting a response following the defeat at Fulham, and we fancy the Whites to pick up all three points on their return to Elland Road courtesy of a narrow success.