Antonio Candreva has been one of his side's standout performers, and has scored in each of the Biancocelesti's last three Serie A matches.
Roma were denied the chance to win their fourth successive league match last weekend, as a waterlogged pitch led to the abandonment of their tie with Parma.
They have slipped nine points behind league leaders Juventus, but kept alive their hopes of claiming glory in this season's Coppa Italia, with a 3-2 win over Napoli in the first leg of their semi-final in midweek.
Possible starting lineups
Lazio: Marchetti, Biava, Cana, Radu, Cavanda, Onazi, Gonzalez, Lulic, Candreva, Keita, Klose
Roma: Sanctis, Maicon, Benatia, Castan, Torosidis, De Rossi, Pjanic, Strootman, Florenzi, Gervinho, Totti
Sports Mole says: 1-1