Walter Mazzarri's team have won just twice in six league games this season, already leaving the Nerazzurri 10 points behind leaders Juventus.
After a slow start to the season, Napoli have begun to turn their form around with wins being registered in their last three fixtures.
Lorenzo Insigne netted the first and assisted the second during that triumph to suggest that he could be ready to find his top form heading into the winter months.
Inter Milan: DWLWL
Possible starting lineups
Inter Milan: Handanovic, Vidic, Dodo, D'Ambrosio, Juan, Hernanes, Medel, M'Vila, Kovacic, Palacio, Icardi
Napoli: Rafael, Albiol, Koulibaly, Maggio, Gargano, Zuniga, Inler, Michu, Higuain, Jose Callejon, Insigne
Sports Mole says: 1-2