Moratti said that he hopes Milan will feel the pressure of being favourites and crumble at the San Siro.
"AC Milan are favourites, without a doubt," ANSA quotes Moratti as saying. "They're the big favourites. They've just beaten Barcelona.
"I don't think I'm saying anything sarcastically, but just because a team are favourites, it doesn't mean they'll necessarily win.
"We just hope the pressure will get to them. It's crucial the players show physical strength and the right spirit to realise it's a very important match for football, for the two clubs' traditions and for the fans."
Inter are currently fifth in Serie A, a point behind their city rivals.