The Nerazzurri will travel to the Juventus Stadium looking for a first win in five games, and Mazzarri believes that they can end Juve's perfect home league record.
"Is the 23-point gap between the sides accurate? That's not for me to say. Are we the underdogs? I don't worry about that either," he told reporters. "If we do everything at the top level, then we can challenge anyone. The result comes from many things and we have to focus on the performance.
"The statistics show the Juventus Stadium helps them to get good results and they always have a strong start on home turf. It is a factor and we considered every element, but as I always say we have to ultimately concentrate on our own football. That is the recipe for success.
"The Bianconeri might seem unbeatable on home turf, but we are fired up and hope to have a great game. I hope some incidents will also go in our favour. We haven't always had the results we deserved this season."
Inter are currently fifth in the Serie A table.