The Tigers currently occupy fifth spot in the Championship table with 25 points from their opening 14 games. Meanwhile, Wolves sit four places lower and with four points fewer than their rivals.
Both teams have suffered inconsistent results in recent weeks, however, with Hull losing three of their last six league games and Wolves losing twice during the same period.
The last match between the two sides came in the Premier League in 2010 when the pair shared the points in a 2-2 draw and Wolves have not beaten Hull since 2007.
Neither side has any fresh injury concerns ahead of the match and both could name the same XI that started their last Championship encounters.
Hull City: LLWWLW
Hull: Amos; Elmohamady, Chester, McShane, Bruce, Rosenior; Evans, Koren, Queinn; Simpson, Aluko
Wolves: Ikeme; Foley, Berra, Johnson, Ward; Pennant, Henry, Sako, Doumbia; Doyle, Ebanks-Blake
Sports Mole says: 2-2