Heracles, meanwhile, are looking to bounce back from the weekend's home defeat to Vitesse and move up from 12th in the table.
Indeed, having finished eighth last season, Heracles have found things tougher this season, taking 15 points from 15 games so far.
Frank Wormuth, who has been in charge since July 2018, appears to be struggling to inject offensive edge into his side, with them only averaging one goal per game and failing to score at all in three of their last seven matches.
Without midfielder Rai Vloet, who has scored seven of the club's 15 league goals, they would likely find themselves embroiled in a relegation battle. However, with a six point cushion and more quality on the books than most of the sides below them, Wormuth will not be panicking just yet.
A home game against bottom-placed Emmen on Tuesday certainly represents an excellent opportunity for Heracles to kickstart their campaign.
Having competed in the Eredivisie for the first time in the club's entire history in the 2018-19 campaign, meanwhile, Emmen's three-year spell in Holland's top flight is at serious risk of coming to an end.
Dick Lukkien's side have failed to win any of their 15 league games this season, drawing five and losing 10 to lie five points from safety.
Lukkien may feel fortunate not to be further entrenched at the foot of the table, taking hope from the fact that the five sides above Emmen are all also averaging less than one point per game so far this season.
If the 48-year-old can tighten up the defence, which has conceded 24 goals in just eight home matches, then they will have an outside chance of extending their time at the elite level.
Heracles Eredivisie form: LDLWWL
Emmen Eredivisie form: LLDDLL
Emmen form (all competitions): LDWDLL
Heracles are likely to be without Navajo Bakboord with a knee injury, but otherwise Wormuth appears to have a full squad to choose from.
Emmen, meanwhile, will remain without Luciano Carty, but also appear to have a fairly small injury list.
Lukkien could opt to make a few changes after the disappointing 4-1 defeat to FC Twente, with Nikolai Laursen likely to come into the side.
Heracles possible starting lineup:
Blaswich; Breukers, Rente, Propper, Quagliata; Schoofs, Vloet, Kiomourtzoglu; Van der Water, Bakis, Burgzorg
Emmen possible starting lineup:
Telgenkamp; Bijl, Araujo, Van Rhijn, Cavlan; Laursen, Bernadou, Veendorp, Pena; Jansen, de Leeuw
We say: Heracles 2-0 Emmen
We can envisage Heracles getting back to winning ways against Emmen, who look devoid of any confidence at present.
The hosts are not exactly free-scoring this season, though, so may have to remain patient and be clinical with the chances which should come their way.