The 23-year-old is expected to start for Roy Hodgson's side in Basel after Daniel Sturridge was ruled out due to injury, and Welbeck has revealed that he is looking to take his chance to cement a place in the team.
"It is always an opportunity to show what you can do. Whoever gets the chance on Monday will be looking to showcase their talent," Welbeck told the FA's official website.
"Switzerland haven't got 12 men, it's 11 v 11. Once we are on that pitch, the main thing is getting that win. We have got to get off to a good start and that is our main focus at the moment."
Switzerland are currently ninth in the FIFA world rankings, 11 places above England.