That brought to an end a six-game winning streak in all competitions, and Mourinho's men must now face a Shrewsbury side that are flying and still unbeaten at home this season.
Micky Mellon's side have won four games on the bounce to climb into the League Two playoff places and will have had an extra day to prepare for the visit of the Blues, who are still yet to suffer defeat in 2014-15.
Mourinho is sure to make a hoard of changes from the side that were held by United on Sunday, with Ramires possibly making his return from a groin injury.
The last time these two sides met was in the FA Cup third round in January 2003. Chelsea won the game 4-0 and current club captain John Terry was part of the team on that day.
Possible starting lineups
Shrewsbury: Leutwiler; Grandison, Goldson, Knight-Percival; Grimmer, Woods, Lawrence, Wesolowski, Demetriou; Collins, Akpa Akpro
Chelsea: Cech; Ake, Zouma, Terry, Luis; Mikel, Baker; Ramires, Willian, Salah; Schurrle
Sports Mole says: 0-3