The attacking quartet of Pedro, Diego Costa, Victor Moses and Eden Hazard survive the cut, while Asmir Begovic, Nathan Ake, Kurt Zouma, Cesc Fabregas, Nathaniel Chalobah, Willian and club captain John Terry are drafted in.
Wolves boss Paul Lambert, meanwhile, has made five changes from the side which lost 1-0 to Wigan Athletic on Tuesday.
Wolverhampton Wanderers: Ikeme, Coady, Batth, Hause, Doherty, Price, Saville, Costa, Edwards, Weimann, Bodvarsson
Subs: Burgoyne, Stearman, Evans, Saiss, Ronan, Enobakhare, Gibbs-White
Chelsea: Begovic, Zouma, Terry, Ake, Moses, Chalobah, Fabregas, Pedro, Willian, Diego Costa, Hazard
Subs: Eduardo, Azpilicueta, Cahill, Kenedy, Kante, Loftus-Cheek, Batshuayi
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