However, the Blues know that an away goal for Atletico at Stamford Bridge would put the visitors in firm control of the contest.
Petr Cech is in line for a shock return for the hosts despite suffering a shoulder injury in the first leg, while Frank Lampard and John Obi Mikel are unavailable through suspension. Nemanja Matic and Mohamed Salah are both cup-tied.
Atletico, who are currently four points clear at the top of the La Liga table, have no fresh injury problems ahead of the match in West London.
Possible starting lineups
Chelsea: Schwarzer; Azpilicueta, Terry, Cahill, Ivanovic; Ramires, Luiz; Oscar, Willian, Hazard; Eto'o
Atletico: Courtois; Juanfran, Miranda, Godin, Felipe Luis; Garcia, Gabi, Tiago, Koke; Villa, Costa
Sports Mole says: 1-1