While the Hatters have recorded four points from their last two fixtures, Brentford make the trip to Kenilworth Road after two games without success.
Before the 2020-21 season got underway, you would have been hard pushed to find anyone who felt that Luton would be ahead of Brentford after eight matches.
However, despite their respective trajectories during the last campaign, it is Nathan Jones's side who have recorded the better results over the past six-and-a-half weeks.
The Hatters appeared to have wasted their opening results by succumbing to three defeats in the space of four matches, failing to score a goal against Watford, Stoke City or Millwall.
The win over Sheffield Wednesday at Hillsbrough appears to be a turning point, however, with Luton now in the mindset of being disappointed with a 1-1 draw against Nottingham Forest in midweek.
Luton now sit just a point adrift of the top six, although Jones and his players will only be focused on earning as many as early points as possible to keep themselves away from a relegation battle.
From Brentford's perspective, Saturday's encounter has taken on greater importance after conceding a late goal to Norwich City on Tuesday evening.
Instead of sitting in seventh place and moving above the Canaries, the London outfit are now at risk of losing ground on the early pacesetters with another disappointing result.
Brentford are having few issues in the final third with their return of 13 goals the third highest in the division, but Thomas Frank needs to see considerable improvements made at the back.
Although the Dane is unlikely to change his style of play, he will demand that his players are more resolute after making a habit of conceding goals at the wrong moments.
Luton Town Championship form: LWLLWD
Brentford Championship form: DLWWLD
Brentford form (all competitions): WLWWLD
The short turnaround may lead to Jones making a couple of alterations to his Luton XI.
Although Pontus Jansson is closing in on a return from a hamstring injury, the centre-back may only feature among the Brentford substitutes.
Luton Town possible starting lineup:
Sluga; Lockyer, Pearson, Bradley; Cranie, Rea, Morrell, Norrington-Davies; Mpanzu, LuaLua; Collins
Brentford possible starting lineup:
Raya; Dalsgaard, Pinnock, Sorensen, Henry; Marcondes, Jensen, Dasilva; Mbuemo, Toney, Canos
We say: Luton Town 1-3 Brentford
Although Frank will be increasingly concerned about his side's lack of consistency, this may be the kind of game that the Bees require to get back on track. Luton should prove to be tough opponents, but it may lead to the visitors raising their level of performance.