The country were making their first appearance at the World Cup finals this summer, but failed to make it out of the group stages.
Speaking after his side's 3-1 win over Iran, Susic told Brazilian newspaper Lancenet: "This was my last game at the World Cup."
"Unfortunately there will not be another one. Sometimes it is a nice feeling to be free of obligations. I can decide my own fate and this is my answer."
Bosnia-Herzegovina will begin their Euro 2016 qualifying campaign against Cyprus on September 9.